The fecundability rate defined: Your fecundability rate is not a fresh chance each month — it is a personal, stable probability per cycle that remains essentially constant assuming no change in underlying factors. The core insight is that the population average tells you nothing about where your individual rate sits.
The Weinberg-Wilcox cumulative probability formula
P(n) = 1 − (1 − p)^n
P(6) = 1 − (1 − 0.20)^6 = ~73.8% after 6 months
P(12) = 1 − (1 − 0.20)^12 = ~93.1% after 12 months
P(6) = 1 − (1 − 0.08)^6 = ~39.7% after 6 months
P(12) = 1 − (1 − 0.08)^12 = ~63.4% after 12 months
The clinical multiplier model: how each factor adjusts your base rate
| Factor |
How It's Measured |
Multiplier on Base Rate |
What Changes the Multiplier |
| Base rate (age-adjusted) |
Age alone (population average) |
1.0× (starting point) |
Under 30: ~25%. 30–34: ~20%. 35–39: ~12–15%. 40+: ~5–8%. |
| Intercourse timing accuracy |
OPK / BBT / cycle tracking |
0.8×–1.2× |
Peak day (day before ovulation) = 1.2× modifier. Random untracked timing = 0.8× or lower. |
| Sperm quality (partner) |
Full semen analysis + DFI |
0.3×–1.0× |
Normal parameters = 1.0×. Mild male factor = 0.7×. Severe oligospermia or high DFI = 0.3× or below. |
| Ovarian reserve (AMH) |
Blood test ng/mL |
0.5×–1.3× |
AMH above age-normal = 1.1–1.3×. Diminished reserve (<1.0 ng/mL at 35) = 0.5–0.7×. |
| Uterine/tubal factor |
Hysterosalpingogram (HSG), sono |
0× (blocked) – 1.0× |
One blocked tube = ~0.5×. Both patent = 1.0×. Submucosal fibroid or polyp = 0.6–0.8×. |
| Thyroid/hormonal baseline |
TSH, prolactin, Day 3 FSH/LH |
0.6×–1.0× |
Elevated TSH (above 2.5) = 0.7×. Elevated prolactin = 0.5–0.8×. Easily corrected with medication. |
| BMI (both partners) |
Height and weight |
0.7×–1.0× |
BMI 20–25 = 1.0×. BMI above 35 or below 18.5 = 0.7–0.8× due to hormonal disruption. Modifiable. |
Worked example: A 36-year-old with regular cycles, no known pathology, partner age 38 with no prior testing
Base rate (age 36, female)~13% / cycle
× Timing accuracy (OPK-tracked)× 1.1
× Sperm quality (untested — assume normal)× 1.0
× Ovarian reserve (AMH not tested — assume age-average)× 1.0
× Uterine factor (no known issues)× 1.0
× Thyroid/hormonal (not tested)× 1.0
~14.3% / cycle
Estimated personal fecundability rate — before testing reveals any hidden modifiers
Cumulative at 6 months: ~58% | Cumulative at 12 months: ~82% | If AMH returns low (modifier 0.6×): drops to ~8.6% / cycle → 40% at 6 months, 65% at 12 months. This is why testing changes the decision about when to escalate.
The "Selective Dropout" Problem: Why Population Statistics Are Misleading for Anyone Past Month 3
Fertility statistics like "80% of couples conceive within 6 months" are based on population cohorts where couples who conceive early exit the study. Those who remain in the study pool are skewed toward lower fecundability — their continued presence is itself evidence of a lower personal rate. This is why the commonly cited statistics feel optimistic to couples who are actively trying and not yet successful: those statistics describe the population at month 1, not the sub-population at month 5. Your relevant comparison group shifts every month you try without success, and the calculator's static percentage does not account for this progressive selection effect.